GPC2-CAR T cells tuned for low antigen density mediate potent
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Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. - Abstract - Europe PMC
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
Mechanisms of Resistance and Treatment of Relapse after CAR T-cell Therapy for Large B-cell Lymphoma and Multiple Myeloma - Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and
BiCisCAR T cells targeting both GPC2 and CD276 show potent NB
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Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma - ScienceDirect
Membrane Proteome Array (MPA), Antibody Specificity Profiling
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation
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